Posts Tagged ‘cancer breast’
Anything that may increase the chance of developing a disease is considered a risk factor. As research has indicated women with certain risk factors are more likely than others to develop breast cancer.
The exact causes for breast cancer are not known. Often doctors cannot explain why one woman may develop breast cancer but another does not. What is known is that bruising, bumping or touching the breast does not cause cancer. Breast cancer is not contagious. It is not caught from others.
There have been studies that have revealed some of the risk factors for breast cancer. Among those risk factors are a womans age, a family or personal history of breast cancer, changes in her breast, changes in her genes and her menstrual history. Other risk factors for breast cancer include a womans race, if she has had radiation therapy to the chest, and her breast density. Still other factors for breast cancer include taking diethylstilbestrol (DES), her being overweight or obese after menopause, not being physically active, and her alcohol consumption.
Breast cancer is not common in women before menopause. As women age their chances for breast cancer development can increase. Breast cancer occurrence is greater for women over age 60.
The chance of a woman developing breast cancer is greater if her mother, sister or daughter has a history of the disease. If a family member developed breast cancer before the age of 40, the risk is even greater for a woman developing breast cancer. Other relatives having breast cancer, either on her maternal or paternal side of the family, can also place a woman at greater risk for developing breast cancer.
Having a personal history of breast cancer can also increase a womans risk. If a woman has had breast cancer in one breast the risk of getting breast cancer in the other breast increase.
Changes in a womans breast can place a woman at risk for breast cancer. Cells in a womans breast may look abnormal under a microscope. Abnormal cells such as atypical hyperplasia and lobular carcinoma in situ (or LCIS) increase a womans risk for breast cancer.
Changes in a womans genes including BRCA1, BRCA2, and others may increase the risk for breast cancer. Tests from family members who have been known to have breast cancer can reveal the presence of specific gene changes in family members. In order to improve the detection of this disease in women who have these changes in their genes health care providers may be able to suggest ways to try to reduce the risk of breast cancer.
A womans menstrual and reproductive history can place a woman at risk for breast cancer. Women having their first menstrual period before age 12 have a greater risk for developing breast cancer. The risk of breast cancer increase the older a woman is when she had her first child. A woman going through menopause after age 55 places her at greater risk for breast cancer. If a woman has never had children she is at a greater risk of breast cancer. Taking menopausal hormone therapy with estrogen plus progestin after menopause appears to increase risks for breast cancer. Studies have shown no link between miscarriage or abortion and risks for breast cancer.
Race is another risk factor for breast cancer. Caucasian women more often than Latina, African or Asian American women are diagnosed with breast cancer.
Radiation therapy performed to the chest, including the breast, before a woman is age 30 is another known risk factor for breast cancer. Studies indicate the younger the age of a woman when she received radiation treatment the higher the risk for breast cancer in later life.
A womans breast tissue is either fatty or dense. Placing them at a higher risk of breast cancer are older women whose mammograms, or breast x-rays, reveal more dense tissue.
Diethylstilbestrol, also known as DES, was given to some pregnant women in the United States during the 1940s until 1971. This is no longer given to pregnant women. Taking DES during pregnancy may slightly increase the risk for breast cancer. The possible effects on the daughters of women who were given DES while pregnant are still being studied.
A woman being overweight or obese after menopause can increase a womans risk for developing breast cancer. Studies have indicated that after menopause the risk increases for women who are overweight.
A physically inactive lifestyle may contribute to risks for breast cancer. If a woman is active it can prevent weight gain and obesity and therefore reduce chances for breast cancer.
Drinking alcohol increases risks for breast cancer. Studies indicate the more alcohol a woman drinks her risk for breast cancer increase.
Researchers are currently studying other possible risk factors for breast cancer. Currently being studied are the effect of diet, genetics, physical activity, and certain environmental substances increasing the risks for breast cancer.
Avoiding known risk factors for breast cancer can help women protect themselves against breast cancer. Risk factors for breast cancer such as family history cannot be avoided. These should be discussed with her doctor.
Most women who have known risk factors do not get breast cancer. Many women with breast cancer do not have a family history of the disease. Most women with breast cancer have no clear sign for risk factors other than growing older.
If a woman thinks she is at risk for breast cancer she should discuss her concern with her doctor. Her doctor may be able to suggest ways she can reduce her risk. At risk or not, a woman should plan scheduled checkups with her health care provider. Prevention is the best cure.
Author: John Marston
Article Source: EzineArticles.com
Provided by: How Electric Pressure Cookers Work
Breast cancer is a largely unknown disease until today, despite the fact that it affects almost ten percent of the women above the age of forty years all over the world. The causes of this killer cancer are not known even after decades of research into it. Similarly it is unknown why some women have higher chances of getting breast cancers than others.
Though the causative factors are not known, some risk factors have been identified. There is no medical proof why these factors make the disease more probable, but this is a study of observation. In a vast cross-section of women with the observed risk factors, it has been found that the chances of getting breast cancers are very high.
The various risk factors for breast cancer are as follows:-
(1) Family History of Breast Cancer
If a near relative like a mother or a sister has had breast cancer, then there is a very high chance that the cancer will occur sometime in life. This propensity is observed even if far relatives such as cousins and aunts have had breast cancer, though the chances are lesser as the relatives are more removed. Even if a male relative has had breast cancer or prostate cancer, then there is a chance of getting breast cancer. This clearly indicates that breast cancer runs through family lines through inheritance. Certainly the chances are very high if more than one family member has had breast cancer.
(2) Personal History of Breast Cancer
If a woman has had breast cancer in the past, then there is a great chance that the breast cancer may recur. This is true even if the cancer had been removed in its benign stage itself. Sometimes the cancer cells spread into the nearby lymph. This makes a possibility that the cancer will occur in the opposite breast. In fact, women who have had cancer in one breast have 50 to 75% more chances of developing the cancer in the other breast.
(3) Diseases of the Breast
Several breast diseases can increase the chances of having breast cancer. Changes in the cells of the breasts can lead to atypical hyperplasia. This condition can cause a three to fourfold increase in the possibility of getting breast cancer in the later years. This risk also exists if the atypical hyperplasia has occurred in other women of the family. Another such condition is the benign breast tumor condition known as fibro adenoma. However, women with fibrocystic breasts generally do not have any added vulnerability to breast cancer. Yet, such conditions could make the breasts lumpy and hide the real tumors (if any) during mammography.
(4) Lifestyle
In todays world, lifestyle is the single largest contributing factor for the proliferation of breast cancer among women. Several elements of the lifestyle have been found to be directly accordant with the prevalence of breast cancer. Smoking and alcoholism in women are among the chief factors. Even diet has been pointed out as an important risk factor. Women who consume a diet with more high-cholesterol fats in them have higher chances of breast cancer. At the same time leading a sedentary lifestyle without indulging much in physical activity are also potentially dangerous.
(5) Radiation
It has been found that women who undergo radiation therapies in their chest region at a young age have an increased risk of developing breast cancer in their later lives. Radiation therapy is generally prescribed for women with conditions like Hodgkins disease or non-Hodgkins lymphoma. So women who have undergone such treatments may get breast cancer in their later years.
(6) Hormonal Imbalances There are several factors that can change the hormone balance of the body. Some of them are:- a) Beginning the menstrual cycle early, i.e. before the age of twelve years, b) Having the first pregnancy after the age of thirty years, c) Having no pregnancy at all, d) Having a late menopause. All these conditions can increase the level of estrogen in the body. This increases the risk of getting breast cancer to a mild extent. Apart from that women who take regular birth control pills, breast enhancement supplements, antidepressants and antihistamines and hormone modifying supplements stand at a higher risk to get breast cancers.
The above are the major risk factors for breast cancers. But since the study on breast cancers is not yet complete, the above is by no means a complete list. There are several other indications of breast cancers, like breast implant operations; but these have not yet been confirmed. The implants used in the earlier days were made of silicone gels. These were riskier in terms of breast cancer. However, nowadays the silicone gel implants have been replaced by saline implants. This has reduced the risk to a great extent.
It must be also noted that women have much higher chances of getting breast cancer than men. In fact, most people think that breast cancer is a disease that affects only women. This is not true. Men also get breast cancers, but to a much lesser degree than women. Also, age is a very important factor. The chances of getting breast cancer are much higher when the woman has crossed the age of 50 years.
Author: Anna Hardy
Article Source: EzineArticles.com
Provided by: Canada duty rate
Why do women fear breast cancer more than any other disease? Because each year thousands of women develop breast cancer in our society and as scary as it sounds the percentage of breast cancer continues to rise. This type of cancer is very common in our society. Nevertheless, with the help of medical technologies breast cancer is now 90% curable when diagnosed early.
We do not know what causes breast cancer, although we do know that certain risk factors may put you at higher risk of developing it. A person’s age, genetic factors, personal health history and diet all contribute to breast cancer risk.
Before I go any further, we need to start at square one. We may know what breast cancer is, but do we really know the entire factors (details) behind the disease? Let us ask ourselves, What is breast cancer?
Breast cancer is when the cells in a womans body begin to grow and reproduce out of control, which creates a collection of tissue called a tumor. However, just because you have a tumor in the breast does not mean it has to be cancerous.
If the cells that are growing out of control are normal cells, the tumor is not cancerous. However, if the cells that are growing out of control are abnormal and does not function like the body’s normal cells, the tumor is cancerous.
Cancers are named after the part of the body from which they originate. Breast cancer originates in the breast tissue. Like other cancers, breast cancer can infect and grow into the tissue surrounding the breast. It can also pass through to other parts of the body and form new tumors. This course of action is called metastasis.
Breast cancer is the most common cancer among American women, after nonmelanoma skin cancer. Over the past 50 years, the number of women diagnosed with the disease has increased each year.
Today, approximately one in almost every eight women (13.4%) will develop breast cancer in her lifetime. Breast cancer is the second-leading cause of cancer death in women after lung cancer. It is the leading cause of cancer death among women ages 35 to 54.
The American Cancer Society estimates that in 2005, approximately 211,240 women will be diagnosed with invasive breast cancer and approximately 40,410 will die. Although these numbers may sound frightening, research tells us that the death rate could decrease by 30% if all women age 50 and older who need a mammogram had one.
Only 5-10% of breast cancers occur in women with a clearly defined genetic predisposition for the disease. The majority of breast cancer is not related to their family history. The risk for developing breast cancer increases as a woman ages.
Below I listed the warning signs of breast cancer. It is important to understand what the disease is and to know the symptoms, so you can get medical attention if necessary.
Look for:
Lump or thickening in, near the breast, or in the underarm that persists through the menstrual cycle.
A mass or lump, which may feel as small as a seed.
A change in the size, shape or contour of the breast.
A bloodstained or clear fluid discharge from the nipple.
A change in the feel or appearance of the skin on the breast or nipple (dimpled, puckered, scaly or inflamed).
Redness of the skin on the breast or nipple.
An area that is distinctly different from any other area on either breast.
A marble-like hardened area under the skin.
These changes may be found when performing monthly breast self-exams. By performing breast self-exams, you can become familiar with the normal monthly changes in your breasts. All doctors stress the importance of breast examinations. The problem is that most women do not know how to give a breast examination to them and instead wait until they see their doctor. By then it could be too late. This is why it is important to learn how to give you a breast examination.
Breast self-examination should be performed at the same time each month, three to five days after your menstrual period ends. If you have stopped menstruating, perform the exam on the same day of the month. To perform a breast self-exam, follow the steps described below.
In the mirror:
1. Stand undressed from the waist up in front of a large mirror in a well-lit room. Look at your breasts. Do not be alarmed if they do not look equal in size or shape. Most women’s breasts are not. With your arms relaxed by your sides, look for any changes in size, shape or position, or any changes to the skin of the breasts. Look for any skin puckering, dimpling, sores or discoloration. Inspect your nipples and look for any sores, peeling or change in the direction of the nipples.
2. Next, place your hands on your hips and press down firmly to tighten the chest muscles beneath your breasts. Turn from side to side so you can inspect the outer part of your breasts.
3. Then bend forward toward the mirror. Roll your shoulders and elbows forward to tighten your chest muscles. Your breasts will fall forward. Look for any changes in the shape or contour of your breasts.
4. Now, clasp your hands behind your head and press your hands forward. Again, turn from side to side to inspect your breasts’ outer portions. Remember to inspect the border underneath your breasts. You may need to lift your breasts with your hand to see this area.
5. Check your nipples for discharge (fluid). Place your thumb and forefinger on the tissue surrounding the nipple and pull outward toward the end of the nipple. Look for any discharge. Repeat on your other breast.
In the shower
6. Now, it is time to feel for changes in the breast. It is helpful to have your hands slippery with soap and water. Check for any lumps or thickening in your underarm area. Place your left hand on your hip and reach with your right hand to feel in the left armpit. Repeat on the other side.
7. Check both sides for lumps or thickenings above and below your collarbone.
8. With hands soapy, raise one arm behind your head to spread out the breast tissue. Use the flat part of your fingers from the other hand to press gently into the breast. Follow an up-and-down pattern along the breast, moving from bra line to collarbone. Continue the pattern until you have covered the entire breast. Repeat on the other side.
Lying down
9. Next, lie down and place a small pillow or folded towel under your right shoulder. Put your right hand behind your head. Place your left hand on the upper portion of your right breast with fingers together and flat. Body lotion may help to make this part of the exam easier.
10. Think of your breast as a face on a clock. Start at 12 o’clock and move toward 1 o’clock in small circular motions. Continue around the entire circle until you reach 12 o’clock again. Keep your fingers flat and in constant contact with your breast. When the circle is complete, move in one inch toward the nipple and complete another circle around the clock. Continue in this pattern until you have felt the entire breast. Make sure to feel the upper outer areas that extend into your armpit.
11. Place your fingers flat and directly on top of your nipple. Feel beneath the nipple for any changes. Gently press your nipple inward. It should move easily.
Repeat steps 9, 10 and 11 on your other breast.
Cancerous tumors are more likely to be found in certain parts of the breast over others. If you divide the breast into 4 sections, the approximate percentage of breast cancers found in each area are (in clockwise pattern):
41% upper, outer quadrant
14% upper, inner quadrant
5% lower, inner quadrant
6% lower, outer quadrant
34% in the area behind the nipple
Almost half occur in the upper outer quadrant of the breast, towards the armpit. Some physicians refer to this region as the “tail” of the breast and encourage women to examine it closely.
See your doctor if you discover any new breast changes, changes that continue after your menstrual cycle, or other changes that you are concerned about such as:
An area that is distinctly different from any other area on either breast.
A lump or thickening in, near the breast, or in the underarm that persists through the menstrual cycle.
A change in the size, shape or contour of the breast.
A mass or lump, which may feel as small as a seed.
A marble-like area under the skin.
A change in the feel or appearance of the skin on the breast or nipple (dimpled, puckered, scaly or inflamed).
Bloody or clear fluid discharge from the nipples.
Redness of the skin on the breast or nipple.
If you go to your doctor and your doctor finds cancer, you and your doctor will develop a treatment plan to eliminate the breast cancer, to reduce the chance of cancer returning in the breast, as well as to reduce the chance of the cancer traveling to a location outside of the breast. Treatment generally follows within a few weeks after the diagnosis.
The type of treatment recommended will depend on the size and location of the tumor in the breast, the results of lab tests done on the cancer cells and the stage or extent of the disease. Your doctor usually considers your age and general health as well as your feelings about the treatment options.
Breast cancer treatments are local or systemic.
Local treatments are used to remove, destroy or control the cancer cells in a specific area, such as the breast. Surgery and radiation treatment are local treatments.
Systemic treatments are used to destroy or control cancer cells all over the body. Chemotherapy and hormone therapy such as tamoxifen, and biologic therapies like Herceptin, are systemic treatments. A patient may have just one form of treatment or a combination, depending on her needs.
Following local breast cancer treatment, the treatment team will determine the likelihood that the cancer will recur outside the breast. This team usually includes a medical oncologist, a specialist trained in using medicines to treat breast cancer. The medical oncologist, who works with the surgeon, may advise the use of tamoxifen or possibly chemotherapy. These treatments are used in addition to, but not in place of, local breast cancer treatment with surgery and/or radiation therapy.
Remember get a mammogram. You should have a baseline mammogram at age 35 and a screening mammogram every year after age 40. Mammograms are an important part of your health history. If you go to another healthcare provider, or move, take the film (mammogram) with you.
Examine your breasts each month after age 20. You will become familiar with the contours and feel of your breasts and will be more alert to changes.
Have your breast examined by a healthcare provider at least once every three years after age 20, and every year after age 40. Clinical breast exams can detect lumps that may not be detected by mammogram. Never be afraid to ask questions. Contact your American Cancer Society that can answer your questions or lead you to the person that can answer your questions.
Author: Stacey Chillemi
Article Source: EzineArticles.com
Provided by: Duty tariff
Breast cancer is the most common malignancy in women and the second leading cause of cancer death, exceeded only by lung cancer in 1985. One woman in eight who lives to age 85 will develop breast cancer at some time during her life.
At present there are over 2 million women living in the United States who have been treated for breast cancer. About 41,000 women will die from the disease. The chance of dying from breast cancer is about 1 in 33. However, the rate of death from breast cancer is going down. This decline is probably the result of early detection and improved treatment.
Breast cancer is not just a womans disease. The American Cancer Society estimates that 1600 men develop the disease yearly and about 400 may die from the disease.
Breast cancer risk is higher among those who have a mother, aunt, sister, or grandmother who had breast cancer before age 50. If only a mother or sister had breast cancer, your risk doubles. Having two first-degree relatives who were diagnosed increases your risk up to five times the average.
Although it is not known exactly what causes breast cancer; sometimes the culprit is a hereditary mutation in one of two genes, called BRCA1 and BRCA2. These genes normally protect against the disease by producing proteins that guard against abnormal cell growth, but for women with the mutation, the lifetime risk of developing breast cancer can increase up to 80 percent, compared with 13 percent among the general population. In effect, more than 25 percent of women with breast cancer have a family history of the disease.
For women without a family history of breast cancer, the risks are harder to identify. It is known that the hormone estrogen feeds many breast cancers, and several factors diet, excess weight, and alcohol consumption can raise the bodys estrogen levels.
Early Signs
Early signs of breast cancer include the following:
- A lump which is usually single, firm and most often painless is detected.
- An area of the skin on the breast or underarm is swollen and has an unusual appearance.
- Veins on the skin surface become more prominent on one breast.
- The affected breast nipple becomes inverted, develops a rash, changes in skin texture, or has a discharge other than breast milk.
- A depression is found in an area of the breast surface.
Types and Stages of Breast Cancer
There are many different varieties of breast cancer. Some are fast-growing and unpredictable, while others develop more slowly and steady. Some are stimulated by estrogen levels in the body; some result from mutation in one of the two previously mentioned genes – BRCA1 and BRCA2.
Ductal Carcinoma In-Situ (DCIS): Generally divided into comedo (blackhead), in which the cut surface of the tumor shows extrusion of dead and necrotic tumor cells similar to a blackhead, and non-comedo types. DCIS is early breast cancer that is confined to the inside of the ductal system. The distinction between comedo and non-comedo types is important, as comedocarcinoma in-situ generally behaves more aggressively and may show areas of micro-invasion through the ductal wall into surrounding tissue.
Infiltrating Ductal: This is the most common type of breast cancer, representing 78 percent of all malignancies. On mammography, these lesions can appear in two different shapes — stellate (star- like) or well circumscribed (rounded). The stellate lesions generally have a poorer prognosis.
Medullary Carcinoma: This malignancy comprises 15 percent of breast cancers. These lesions are generally well circumscribed and may be difficult to distinguish from fibroadenoma by mammography or sonography. With this type of breast cancer, prognostic indicators estrogen and progesterone receptor are negative 90 percent of the time. Medullary carcinoma usually has a better prognosis than other types of breast cancer.
Infiltrating Lobular: Representing 15 percent of breast cancers, these lesions generally appear in the upper outer quadrant of the breast as a subtle thickening and are difficult to diagnose by mammography. Infiltrating lobular can involve both breasts (bilateral). Microscopically, these tumors exhibit a linear array of cells and grow around the ducts and lobules.
Tubular Carcinoma: This is described as orderly or well-differentiated carcinoma of the breast. These lesions make up about 2 percent of breast cancers. They have a favorable prognosis with nearly a 95 percent 10-year survival rate.
Mucinous Carcinoma: Represents 1-2 percent of carcinoma of the breast and has a favorable prognosis. These lesions are usually well circumscribed (rounded).
Inflammatory Breast Cancer: This is a particularly aggressive type of breast cancer that is usually evidenced by changes in the skin of the breast including redness (erythema), thickening of the skin and prominence of the hair follicles resembling an orange peel. The diagnosis is made by a skin biopsy, which reveals tumors in the lymphatic and vascular channels about 50 percent of the time.
Stages of Breast Cancer
The most common type of breast cancer is ductal carcinoma. It begins in the lining of the ducts. Another type, called lobular carcinoma, arises in the lobules. When cancer is found, the pathologist can tell what kind of cancer it is – whether it began in a duct (ductal) or a lobule (lobular) and whether it has invaded nearby tissues in the breast (invasive).
When cancer is found, special lab tests of the tissue are usually done to learn more about the cancer. For example, hormone (estrogen and progesterone) receptor tests can help determine whether hormones help the cancer to grow. If test results show that hormones do affect the growth of the cancer (a positive test result), the cancer is likely to respond to hormonal therapy. This therapy deprives the cancer cells of estrogen.
Other tests are sometimes done to help predict whether the cancer is likely to progress. For example, x-rays and other lab tests are done. Sometimes a sample of breast tissue is checked for a gene, known as the human epidermal growth factor receptor-2 (HER-2 gene) that is associated with a higher risk that the breast cancer will recur. Special exams of the bones, liver, or lungs are done because breast cancer may spread to these areas.
A woman’s treatment options depend on a number of factors. These factors include her age and menopausal status; her general health; the size and location of the tumor and the stage of the cancer; the results of lab tests; and the size of her breast. Certain features of the tumor cells, such as whether they depend on hormones to grow are also considered.
In most cases, the most important factor is the stage of the disease. The stage is based on the size of the tumor and whether the cancer has spread. The following are brief descriptions of the stages of breast cancer and the treatments most often used for each stage. Other treatments may sometimes be appropriate.
Stage 0
Stage 0 is sometimes called non-invasive carcinoma or carcinoma in situ. Lobular carcinoma in situ (LCIS) refers to abnormal cells in the lining of a lobule. These abnormal cells seldom become invasive cancer. However, they are an indicator of an increased risk of developing breast cancer in both breasts. The treatment for LCIS is a drug called tamoxifen, which can reduce the risk of developing breast cancer. A person who is affected may choose not to have treatment, but to monitor the situation by having regular checkups. And occasionally, the decision is made to have surgery to remove both breasts to try to prevent cancer from developing. In most cases, removal of underarm lymph nodes is not necessary.
Ductal carcinoma in situ (DCIS) refers to abnormal cells in the lining of a duct. DCIS is also called intraductal carcinoma. The abnormal cells have not spread beyond the duct to invade the surrounding breast tissue. However, women with DCIS are at an increased risk of getting invasive breast cancer. Some women with DCIS have breast-sparing surgery followed by radiation therapy. Alternatively, they may choose to have a mastectomy, with or without breast reconstruction (plastic surgery) to rebuild the breast. Underarm lymph nodes are not usually removed. Also, women with DCIS may want to talk with their doctor about tamoxifen to reduce the risk of developing invasive breast cancer.
Stage I and II
Stage I and stage II are early stages of breast cancer in which the cancer has spread beyond the lobe or duct and invaded nearby tissue.
Stage I means that the tumor is about one inch across and cancer cells have not spread beyond the breast.
Stage II means one of the following:
The tumor in the breast is less than 1 inch across and the cancer has spread to the lymph nodes under the arm.
The tumor is between 1 and 2 inches (with or without spread to the lymph nodes under the arm).
The tumor is larger than 2 inches but has not spread to the lymph nodes under the arm.
The treatment options for early stage breast cancer are breast-sparing surgery followed by radiation therapy to the breast, and mastectomy, with or without breast reconstruction to rebuild the breast. These approaches are equally effective in treating early stage breast cancer. (Sometimes radiation therapy is also given after mastectomy.)
The choice of breast-sparing surgery or mastectomy depends mostly on the size and location of the tumor, the size of the breast, certain features of the cancer, and how the person feels about preserving the breast. With either approach, lymph nodes under the arm usually are removed.
Chemotherapy and/or hormonal therapy after primary treatment with surgery or surgery and radiation therapy are recommended for stage I and most frequently with stage II breast cancer. This added treatment is called adjuvant therapy. Systemic therapy sometimes given to shrink the tumor before surgeries called neoadjuvant therapy. This is given to try to destroy any remaining cancer cells and prevent the cancer from recurring, or coming back, in the breast or elsewhere.
Stage III
Stage III is also called locally advanced cancer. In this stage, the tumor in the breast may exhibit the following:
More than 2 inches across and the cancer has spread to the underarm lymph nodes.
The cancer is extensive in the underarm lymph nodes.
The cancer is spreading to lymph nodes near the breastbone or to other tissues near the breast.
Inflammatory breast cancer is a type of locally advanced breast cancer. In this type of cancer, the breast looks red and swollen (or inflamed) because cancer cells block the lymph vessels in the skin of the breast.
Patients with stage III breast cancer usually have both local treatment to remove or destroy the cancer in the breast and systemic treatment to stop the disease from spreading. The local treatment may be surgery and/or radiation therapy to the breast and underarm. The systemic treatment may be chemotherapy, hormonal therapy, or both. Systemic therapy may be given before local therapy to shrink the tumor or afterward to prevent the disease from recurring in the breast or elsewhere.
Stage IV
Stage IV is metastatic cancer. The cancer has spread beyond the breast and underarm lymph nodes to other parts of the body.
The treatments for stage IV breast cancer are chemotherapy and/or hormonal therapy to destroy cancer cells and control the disease. Patients may have surgery or radiation therapy to control the cancer in the breast. Radiation may also be useful to control tumors in other parts of the body.
Recurrent Cancer
Recurrent cancer means the disease has returned in spite of the initial treatment. Even when a tumor in the breast seems to have been completely removed or destroyed, the disease sometimes returns because undetected cancer cells remained somewhere in the body after treatment.
Most recurrences appear within the first 2 or 3 years after treatment, but breast cancer can recur many years later.
Cancer that returns only in the area of the surgery is called a local recurrence. If the disease returns in another part of the body, the recurrence is called metastatic breast cancer. The patient may have one type of treatment or a combination of treatments for recurrent cancer.
For more information, see “Nine Ways to Reduce Breast Cancer Risk” on this site.
Sources: National Cancer Institute; Centers for Disease Control
Author: Syble James
Article Source: EzineArticles.com
Provided by: Digital Camera News
Cancer accounts to a death of 6 million human lives per year. Modern medicine is aging with breath taking advances in cancer care with increasing awareness, preventing, detection, therapy, research and symptom management. Last 15 years has been a revolution. It is likely to fight Cancer out by getting an early detection especially at a pre cancer stage thus yielding best cure with much shorter treatment time, lesser cost, lesser body insult.
Am I at risk for breast cancer? Breast cancer is the most common malignancy-affecting woman in North America and Europe. Every woman is at risk for breast cancer. Close to 200,000 cases of breast cancer were diagnosed in the United States in 2001. Breast cancer is the second leading cause of cancer death in American women behind lung cancer. The lifetime risk of any particular woman getting breast cancer is about 1 in 8 although the lifetime risk of dying from breast cancer is much lower at 1 in 28. The diagnosis once confirmed by Doctor shocks in such a way that not only the patient suffers but entire family suffers the shock. Thus the patient and family both suffer differently and that adds to the total burden of cancer related illness.
Know your breast: The breast is a collection of glands and fatty tissue that lies between the skin and the chest wall. The glands inside the breast produce milk after a woman has a baby. Each gland is called as lobule and many such lobules make up a lobe. There are 15 to 20 lobes in each breast. The milk gets to the nipple from the glands by way of tubes called ducts. The glands and ducts get bigger when a breast is filled with milk, but the tissue that is most responsible for the size and shape the breast is the fatty tissue. There are also blood vessels and lymph vessels in the breast. Lymph is a clear liquid waste product that gets drained out of the breast into lymph nodes. Lymph nodes are small, pea-sized pieces of tissue that filter and clean the lymph. Most lymph nodes that drain the breast are under the arm in what is called the axilla.
Risk factors for breast cancer: They can be divided into those that you cannot change and those that you can change. Some factors that increase your risk of breast cancer that you cannot alter include being a woman, getting older, having a family history (having a mother, sister, or daughter with breast cancer doubles your risk), having a previous history of breast cancer, having had radiation therapy to the chest region, being Caucasian, getting your periods young (before 12 years old), having your menopause late (after 50 years old), never having children or having them when you are older than 30, and having a genetic mutation that increases your risk. Genetic mutations for breast cancer have become a hot topic of research lately. Between 3-10% of breast cancers may be related to changes in either the gene BRCA1 or the gene BRCA2.
Women can inherit these mutations from their parents and it may be worth testing for either mutation if a woman has a particularly strong family history of breast cancer (meaning multiple relatives affected, especially if they are under 50 years old when they get the disease). If a woman is found to carry either mutation, she has a 50% chance of getting breast cancer before she is 70. Family members may elect to get tested to see if they carry the mutation as well. If a woman does have the mutation, she can get more rigorous screening or even undergo preventive (prophylactic) mastectomies to decrease her chances of contracting cancer. The decision to get tested is a highly personal one that should be discussed with a doctor who is trained in counseling patients about genetic testing.
Certain factors which increase a woman’s risk of breast cancer can be altered including taking hormone replacement therapy (long term use of estrogens with progesterone for menopause symptoms slightly increases your risk), taking birth control pills (a very slight increased risk that disappears in women who have stopped them for over 10 years), not breastfeeding, drinking 2 to 5 alcoholic drinks a day, being overweight (especially after menopause), and not exercising. All of these modifiable risk factors are not nearly as important as gender, age, and family history, but they are things that a woman can control that may reduce her chances of developing a breast malignancy. Remember that all risk factors are based on probabilities, and even someone without any risk factors can still get breast cancer. Proper screening and early detection are our best weapons in reducing the mortality associated with this disease.
What are the signs of breast cancer? Unfortunately, the early stages of breast cancer may not have any symptoms. This is why it is important to follow screening recommendations. As a tumor grows in size, it can produce a variety of symptoms including: lump or thickening in the breast or underarm, change in size or shape of the breast, nipple discharge or nipple turning inward, redness or scaling of the skin or nipple, ridges or pitting of the breast skin
Can you prevent breast cancer? The individual cannot control the most important risk factors for the development of breast cancer. There are some risk factors that are associated with an increased risk, but there is not a clear cause and effect relationship. In no way can strong recommendations be made like the cause and effect relationship seen with tobacco and lung cancer. There are a few risk factors that may be modified by a woman that potentially could influence the development of breast cancer. If possible, a woman should avoid long-term hormone replacement therapy, have children before age 30, breastfeed, avoid weight gain through exercise and proper diet, and limit alcohol consumption to 1 drink a day or less. For women already at a high risk, their risk of developing breast cancer can be reduced by about 50% by taking a drug called Tamoxifen for five years. Tamoxifen has some common side effects (like hot flashes and vaginal discharge), which are not serious and some uncommon side effects (like blood clots, pulmonary embolus, stroke, and uterine cancer) which are life threatening. Tamoxifen isn’t widely used for prevention, but may be useful in some cases.
There are limited data suggesting that vitamin A may protect against breast cancer but further research is needed before it can be recommended for prevention. Other things being investigated include phyto estrogens (naturally occurring estrogens that are in high numbers in soy), vitamin E, vitamin C, and other drugs. Further testing of these substances is also needed before they can be recommended for breast cancer prevention. Right now, the most important thing any woman can do to decrease her risk of dying from breast cancer is to have regular mammogram screening, perform breast self-exams once a month. Follow a few, easy steps, you will soon know what is normal for you and will quickly be aware of any changes. If you find a lump or other change, note down where it is and make an appointment to see your doctor as soon as possible.
Question for young womens are how to look? Well it is medically suggested that you stand up straight in front of a mirror with your arms loosely by your sides. Raise your arms above your head and move from side to side so you can see your breasts in the mirror, from different angles. What should you look for? A change in the size of either breast, change in the shape or position of nipple, bleeding or discharge from the nipples, unusual dimpling or puckering.
How do you feel for changes? Lie flat on your back with your head on a pillow. Put a folded towel under the shoulder on the side of the breast you are checking. This helps to spread the tissue so that it is easier to feel. Examine one breast at a time. Put the hand on the same side of the breast that you are going to examine under your head. With your other hand flat and fingers together, use the flats of your fingers to feel around the breast in small, circular movements, in an anticlockwise direction. Cover the whole of the breast including the nipple. Check your armpit for lumps in the same way, starting in the hollow and moving down towards the breast.
Now examine the other breast in the same way. If you think you have found something, feel the same area on the opposite breast. If they are the same it’s probably just your shape, but if you are at all worried, do visit your doctor. Breast cancer happens when cells in the breast begin to grow out of control and can then invade nearby tissues or spread throughout the body. Large collections of this out of control tissue are called tumors. However, some tumors are not really cancer because they cannot spread or threaten someone’s life. These are called benign tumors. The tumors that can spread throughout the body or invade nearby tissues are considered cancer and are called malignant tumors. Theoretically, any of the types of tissue in the breast can form a cancer, but usually it comes from either the ducts or the glands. Because it may take months to years for a tumor to get large enough to feel in the breast, we screen for tumors with mammograms, which can sometimes see disease before we can feel it.
The earlier that a breast cancer is found, the more likely it is that treatment can be curable. Screening mammograms are simply x-rays of each breast. The breast is placed between two plates for a few seconds while the x-rays are taken. If something appears abnormal, or better views are needed, magnified views or specially angled films are taken during the mammogram. Mammograms often detect tumors before they can be felt and they can also identify tiny specks of calcium that could be an early sign of cancer. Regular screening mammograms can decrease the mortality of breast cancer by 30%. Woman should get a yearly mammogram starting at age 40 (although some groups recommend starting at 50), and women with a genetic mutation that increases their risk or a strong family history may want to begin even earlier. Between the ages of 20 and 39, every woman should have a clinical breast exam every 3 years and after age 40 every woman should have a clinical breast exam done each year.
There are some experimental screening modalities that are currently being studied. These include MRI, ductal lavage, ultrasound, optical tomography, PET scan, and digital mammograms. Depending on the results of the mammograms and/or ultrasounds, your doctors may recommend that you get a biopsy. A biopsy is the only way to know for sure if you have cancer, because it allows your doctors to get cells that can be examined under a microscope. There are different types of biopsies; they differ on how much tissue is removed. Some biopsies use a very fine needle, while others use thicker needles or even require a small surgical procedure to remove more tissue. Your team of doctors will decide which type of biopsy you need depending on your particular breast mass. Once the tissue is removed, a pathologist will review the specimen. The pathologist can tell if it is cancer or not; and if it is cancerous, then the pathologist will characterize it by what type of tissue it arose from, how abnormal it looks (known as the grade), whether or not it is invading surrounding tissues, and if the entire lump was excised, the pathologist can tell if there are any cancer cells left at the borders (also known as the margins). The pathologist will also test the cancer cells for the presence of estrogen and progesterone receptors as well as a receptor known as HER-2/neu. Basic 4 stages of breast cancer are called as
Stage 0 (called carcinoma in situ) Lobular carcinoma in situ (LCIS) refers to abnormal cells lining a gland in the breast. Ductal carcinoma in situ (DCIS) refers to abnormal cells lining a duct.
Stage I – early stage breast cancer where the tumor is less that 2 cm across and hasn’t spread beyond the breast
Stage II – early stage breast cancer where the tumor is either less than 2 cm across and has spread to the lymph nodes under the arm; or the tumor is between 2 and 5 cm (with or without spread to the lymph nodes under the arm); or the tumor is greater than 5 cm and hasn’t spread outside the breast
Stage III – locally advanced breast cancer where the tumor is greater than 5 cm across and has spread to the lymph nodes under the arm; or the cancer is extensive in the underarm lymph nodes; or the cancer has spread to lymph nodes near the breastbone or to other tissues near the breast
Stage IV – metastatic breast cancer where the cancer has spread outside the breast to other organs in the body
Depending on the stage of your cancer, your doctor may want additional tests to see if you have metastatic disease. If you have a stage III cancer, you will probably get a chest x-ray, CT scan and bone scan to look for metastases. Each patient is an individual and your doctors will decide what is necessary to adequately stage your cancer.
What are the treatments for breast cancer?
Surgery: Almost all women with breast cancer will have some type of surgery in the course of their treatment while some women will be candidates for what is called breast conservation therapy (BCT) where surgeons perform a lumpectomy which means they remove the tumor with a little bit of breast tissue around it but do not remove the entire breast. Some patients will have a sentinel lymph node biopsy procedure first to determine if a formal lymph node dissection is required. Sometimes, the surgeon will remove a larger part (but not the whole breast), and this is called a segmental or partial mastectomy. Most patients with DCIS that have a lumpectomy are treated with radiation therapy to prevent the local recurrence of DCIS.More advanced breast cancers are usually treated with a modified radical mastectomy. Modified radical mastectomy means removing the entire breast and dissecting the lymph nodes under the arm.
Chemotherapy: is the use of anti-cancer drugs that go throughout the entire body. The higher the stage of cancer you have, the more important it is that you receive chemotherapy; however, even stage I patients may benefit from chemotherapy in certain cases. In early stage patients, the risk of recurrence may be small, and thus the benefits of the chemotherapy are even smaller. There are many different chemotherapy drugs, and they are usually given in combinations for 3 to 6 months after you receive your surgery. Depending on the type of chemotherapy regimen you receive, you may get medication every 3 or 4 weeks; and you may have to go to a clinic to get the chemotherapy because many of the drugs have to be given through a vein. Two of the most common regimens are AC (doxorubicin and cycolphosphamide) for 3 months or CMF (cycolphosphamide, methotrexate, and fluorouracil) for 6 months. There are advantages and disadvantages to each of the different regimens that your medical oncologist will discuss with you. Based on your own health, your personal values and wishes, and side effects you may wish to avoid, you can work with your doctors to come up with the best regimen for your lifestyle.
Radiotherapy: uses high-energy rays (similar to x-rays) to kill cancer cells. It comes from an external source, and it requires patients to come in 5 days a week for up to 6 weeks to a radiation therapy treatment center. The treatment takes just a few minutes, and it is painless. Radiation therapy is used in all patients who receive breast conservation therapy (BCT). It is also recommended for patients after a mastectomy that had large tumors, lymph node involvement, or close/positive margins after the surgery. Radiation is important in reducing the risk of local recurrence and is often offered in more advanced cases to kill tumor cells that may be living in lymph nodes.
Hormonal Therapy: When the pathologist examines your tumor specimen, he or she finds out if the tumor is expressing estrogen and progesterone receptors. Patients whose tumors express estrogen receptors are candidates for therapy with an estrogen-blocking drug called Tamoxifen. Tamoxifen is taken by pill form for 5 years after your surgery. This drug has been shown to drastically reduce your risk of recurrence if your tumor expresses estrogen receptors. However, there are side effects commonly associated with Tamoxifen including weight gain, hot flashes and vaginal discharge that patients may be bothered by. There are also very uncommon side effects like blood clots, strokes, or uterine cancer that may scare patients from choosing to take it. You need to remember that your chances of having a recurrence of your cancer are usually higher than your chances of having a serious problem with Tamoxifen, but the decision to undergo hormonal therapy is a personal one that you should make with your doctor. There are also newer drugs, called aromatase inhibitors that act by decreasing your body’s supply of estrogen; these drugs are reserved for patients who have already gone through menopause. Talk to your doctors about these new therapies.
Biologic Therapy: The pathologist also examines your tumor for the presence of HER-2/neu over expression. A compound called Herceptin (or Trastuzumab) is a substance that blocks this receptor and helps stop the breast cancer from growing.
Follow-up testing: Once a patient has been treated for breast cancer, they need to be closely followed for a recurrence. At first, you will have follow-up visits every 3-4 months. The longer you are free of disease, the less often you will have to go for checkups. After 5 years, you could see your doctor once a year. You should have a mammogram of the treated and untreated breasts every year. Because having had breast cancer is a risk factor for getting it again, having your mammograms done every year is extremely important. If you are taking Tamoxifen, it is important that you get a pelvic exam each year and report any abnormal vaginal bleeding to your doctor.
Drink Green Tea: Generations of families in India and Asia have been turning to tea to cure what ails them. Green tea could benefit at least five vital organs, including the heart. Earlier, green tea was thought to improve urinary and brain function, combat beriberi disease, and alleviate indigestion. In other words, green tea was considered to be a multi-purpose elixir, able to treat a wide variety of health problems. But this ancient remedy has now found a place in modern scientific literature, thanks to a new wave of studies on the medicinal properties of green tea. While studies on human subjects have been inconclusive, initial evidence from the laboratory looks incredibly promising.
While green tea can be beneficial in attacking everything from high cholesterol to depression, it has perhaps gotten the most attention for its impact on cancer.
Antioxidants are important because they can stop the enzyme activities that give rise to cancer. In essence, they repair DNA problems that have been caused by oxidants or free radicals. Green tea has been considered a godsend for good health because it contains antioxidants known as catechins. These substances have been called impressive inhibitors of cancer growth. Heres how they do it: lab tests show that they combat oxidants prior to cell injuries, stop the growth of tumor cells, and reduce the occurrence of tumors.
This article is meant to give you a better understanding of breast cancer. Use this knowledge when meeting with your physician, making treatment decisions, and continuing your search for information.
Stay Healthy, as Health is Wealth!
Author: Joydeep Guha Dam
Article Source: EzineArticles.com
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Lung cancer is among the most common cancers in the Western world. Lung cancer occurs due to the growth of malignant or abnormal cells in the lung. It is the third most common cancer in males and the fifth in females. Yet lung cancer is increasingly becoming a woman’s problem. The risk for dying of lung cancer is 20 times higher among women who smoke two or more packs of cigarettes per day than among women who do not smoke at all. Lung cancer is a cancer that originates in the tissues of the lungs. It can be very difficult to detect at an early stage because the symptoms often do not appear until the disease is far advanced.
Health experts say more needs to be done to educate women about the risk of lung cancer. Bearing in mind that breast cancer is the most commonly diagnosed cancer in women, studies show that since 1987, more women have died each year of lung cancer than from breast cancer. Researchers have found that women who had one or more children had nearly a 40 percent lower risk of contracting lung cancer compared to women without children. Recently, research has suggested that women who don’t smoke are two to three times more likely than non-smoking men to develop lung cancer. In women, the three types of cancer most commonly seen are breast cancer, lung cancer, and colon cancer. Breast cancer is the second leading cause of cancer-related deaths in women (behind lung cancer), and the most common cancer in women.
Lung cancer kills more people than breast or prostate cancer, primarily because by the time it is detected, lung cancer is usually in an advanced stage. Also when cancer spreads to the lung from the breast, the resulting cells are breast cancer cells, not lung cancer cells. Breast cancer is the second leading cause of cancer death in American women behind lung cancer, yet surveys have shown that women are more worried about getting breast cancer than lung cancer. Breast cancer has surpassed lung cancer as the leading cause of cancer death in women worldwide, accounting for more than 400000 deaths per year.
Today there are many treatment options available to lung cancer patients. The type of treatment for lung cancer depends on the cancer’s specific type, how far it has actually spread, and the patient’s status. It is important to know the stage in order to plan treatment. Treatment for a secondary lung cancer depends on the primary cancer. However, new anti-cancer drugs, improved staging and imaging techniques, combined with new surgical procedures have all contributed to dealing with the disease. Finding early-stage lung cancers is crucial in the treatment results for lung cancer. While having treatment for any stage of lung cancer, you will be able to manage some side effects that may accompany lung cancer or any cancer treatment.
Summary:
Lung cancer is the uncontrolled growth of abnormal cells in the lung. We already know that the best way to prevent lung cancer is to quit or never start to smoke in the first place. Small cell lung cancer is a bit more common in men than women. But lung cancer is increasingly becoming a woman’s problem. The links between your smoking history and lung cancer is clear. Lung cancer is the most commonly diagnosed cancer in the world. It is the most deadly of cancers worldwide, resulting in up to 3 million deaths annually.
Author: Ben O’Rourke
Article Source: EzineArticles.com
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